New quinone-amino acid conjugates linked via a vinylic spacer

Authors
Alnabari, M Bittner, S
Citation
M. Alnabari et S. Bittner, New quinone-amino acid conjugates linked via a vinylic spacer, AMINO ACIDS, 20(4), 2001, pp. 381-387
Citations number
22
Categorie Soggetti
Biochemistry & Biophysics
Journal title
AMINO ACIDS
ISSN journal
09394451 → ACNP
Volume
20
Issue
4
Year of publication
2001
Pages
381 - 387
Database
ISI
SICI code
0939-4451(2001)20:4<381:NQACLV>2.0.ZU;2-5
Abstract
Chloranil and 2,3-dichloro-1,4-naphthoquinone have been linked to different natural and unnatural amino acids via a vinylic spacer. Two routes were de veloped for the facile preparation of these novel modified amino acids: the direct method, which can only be applied to secondary amines, and the indi rect method (transamination reaction), which can be applied to any amino ac id or ester.