Therapeutic implications of inflammation in atherosclerotic cardiovasculardisease

Citation
Ch. Selzman et al., Therapeutic implications of inflammation in atherosclerotic cardiovasculardisease, ANN THORAC, 71(6), 2001, pp. 2066-2074
Citations number
64
Categorie Soggetti
Cardiovascular & Respiratory Systems","Medical Research Diagnosis & Treatment
Journal title
ANNALS OF THORACIC SURGERY
ISSN journal
00034975 → ACNP
Volume
71
Issue
6
Year of publication
2001
Pages
2066 - 2074
Database
ISI
SICI code
0003-4975(200106)71:6<2066:TIOIIA>2.0.ZU;2-N
Abstract
Atherosclerosis represents a spectrum of pathologic lesions with diverse cl inical sequelae. In this review, we build upon the paradigm that arterioscl erosis represents an inflammatory disease. By examining mechanisms involved in the response to vascular injury, we can more effectively implement targ eted therapy aimed at halting or regressing arteriosclerosis. (C) 2001 by T he Society of Thoracic Surgeons.