What drugs are our frail elderly patients taking? Do drugs they take or fail to take put them at increased risk of interactions and inappropriate medication use?
C. Frank et al., What drugs are our frail elderly patients taking? Do drugs they take or fail to take put them at increased risk of interactions and inappropriate medication use?, CAN FAM PHY, 47, 2001, pp. 1198-1204
OBJECTIVE To determine whether there were discrepancies between what medica
tions frail elderly outpatients took and what physicians thought they took
and whether discrepancies put patients at risk of taking inappropriate drug
s and of increasing the potential for drug interactions.
DESIGN Case series.
SETTING Day Hospital Program at St Mary's of the Lake Hospital in Kingston,
Ont.
PARTICIPANTS One hundred twenty community-living elderly patients attending
the Day Hospital Program in 1998. Three patients and two family physicians
declined to participate.
MAIN OUTCOME MEASURES Lists of medications being taken by patients compared
with lists of medications in physicians' charts. Category according to exp
licit criteria that each drug fell into and risk of drug interactions as de
termined by the Clinidata Drug Interaction Program.
RESULTS Of the 120 patients, 115 had at least one discrepancy between their
lists of medications and their physicians' lists. Of the 1390 medications
on the lists, 521 (37%) were being taken by patients without their doctors'
knowledge, 82 (6%) were not being taken by patients when doctors thought t
hey were, and 133 (10%) were on both patients' and their doctors' lists but
with dosages or frequency of administration that were different. More pote
ntial drug interactions were identified on patients' lists than on physicia
ns' lists. No increase in risk of inappropriate drug use was identified.
CONCLUSION Family physicians are often unaware of all the medications their
patients are actually taking. Medications used by patients without physici
ans' knowledge increase the likelihood of drug interactions. Family physici
ans should look at and inquire about all medications, including over-the-co
unter drugs, their patients are actually taking.