Objective: To investigate the effect of percutaneous drainage on liver hyda
tid cysts. Design: A retrospective case study. Setting: Department of Surge
ry, Selcuk University, Konya, Turkey. Patients: Forty-five patients with 83
liver hydatid cysts (types I and II according to the classification of Gha
rbi and colleagues) followed up for a mean of 30 months (range from 14 to 3
6 months). Intervention: The cysts were drained percutaneously with ultraso
nographic guidance and then irrigated with 0.05% silver nitrate solution th
rough a fine needle. Albendazole was administered 48 hours before percutane
ous drainage and for 2 months after the procedure to prevent the implantati
on of spilled scolices. Main outcome measures: Complications of the procedu
re, decrease in size of the cyst cavity, recurrence and dissemination of th
e cysts. Results: Ail the cysts were treated successfully by percutaneous d
rainage. Anaphylactic shock developed in 1 (2.2%) patient, and mild allergi
c reactions were observed in 2 (4.4%) patients during the interventional pr
ocedure. Follow-up ultrasonography and CT demonstrated a statistically sign
ificant (p < 0.01) decrease in the mean cyst size. Recurrence and dissemina
tion were not observed during the follow-up period. Conclusion: Percutaneou
s fine-needle aspiration and drainage ius effective for managing cystic liv
er hydatid disease in selected cases.