Jl. Afonso et Mj. Clifton, Coupling between transfer phenomena in continuous-flow electrophoresis: effect on the steadiness of the carrier flow, CHEM ENG SC, 56(10), 2001, pp. 3053-3064
A numerical model of the buffer flow in continuous-flow electrophoresis has
been developed to study the coupling between transfer phenomena (hydrodyna
mics, heat transfer and mass transfer) and their role in inducing natural c
onvection that disturbs the required forced convection. The main theoretica
l unknown in this system is the behaviour of the ion-exchange membranes ope
rating at currents beyond the limiting current. Comparison of the model pre
dictions with experimental observations shows that the traditional water-sp
litting model is definitely superior to the more recent explanation in term
s of electroconvection. (C) 2001 Elsevier Science Ltd. All rights reserved.