Intracellular Ca2+ pools in neuronal signalling

Authors
Citation
R. Rizzuto, Intracellular Ca2+ pools in neuronal signalling, CUR OP NEUR, 11(3), 2001, pp. 306-311
Citations number
72
Categorie Soggetti
Neurosciences & Behavoir
Journal title
CURRENT OPINION IN NEUROBIOLOGY
ISSN journal
09594388 → ACNP
Volume
11
Issue
3
Year of publication
2001
Pages
306 - 311
Database
ISI
SICI code
0959-4388(200106)11:3<306:ICPINS>2.0.ZU;2-D
Abstract
Different intracellular pools participate in generating Ca2+ signals in neu ronal cells and in shaping their spatio-temporal patterns. They include the endoplasmic reticulum (endowed with different classes of Ca2+ channels, wi th distinct functional properties and highly defined expression patterns in the brain), the Golgi apparatus, and the mitochondria. The release of Ca2 from intracellular pools plays an important role in controlling processes such as neurite outgrowth, synaptic plasticity, secretion and neurodegenera tion.