Surgery is the cornerstone of management of epithelial ovarian cancer and h
as broad applications throughout the clinical course of disease, from initi
al diagnosis to palliative care. Comprehensive surgical staging is essentia
l for precise prognostic determination and treatment planning for patients
with apparent early-stage ovarian cancer. Although randomized trials are la
cking, the survival advantage associated with optimal primary cytoreduction
has been consistent and reproducible. With increasing radicality of cytore
ductive surgical techniques and sophistication of postoperative care. it ap
pears that an "optimal" surgical procedure is that which leaves the patient
with no visible residual disease, The survival benefits of cytoreductive s
urgery are also applicable to women with stage IV ovarian cancer, although
the rate of success is somewhat attenuated compared with patients with stag
e III disease. Recent data also indicate that with appropriate surgical sel
ection criteria, secondary cytoreduction is associated with a significant p
rolongation of survival for patients with recurrent ovarian cancer. Unfortu
nately. several recent publications illustrate how the decentralization of
health care may have significant ramifications on the ability of women with
known or suspected ovarian cancer to avail themselves of the surgical stan
dard of care. Curr Opin Oncol 2000, 12:474-480 (C) 2000 Lippincott Williams
& Wilkins, inc.