Anthrax, caused by the spore-forming bacterium Bacillus anthracis, is rarel
y seen in industrial nations but is common in developing countries. Cutaneo
us anthrax (CA), the most common form of the disease, accounts for 95% of c
ases and usually develops on exposed sites. This study reviews the clinical
and laboratory findings of 21 patients diagnosed with CA during 2 separate
epidemics in the Van region of Turkey. All patients had a history of direc
t contact with infected cattle. The patients, aged 1.5 to 64 years, include
d 13 females and 8 mates. Of the patients, 9 were 15 years or younger. Skin
lesions were localized on the hands and fingers in 15 patients, on the fac
e in 3 patients, on the face and finger in 1 patient, on the chest and-fing
er in 1 patient, and on the eyelid in 1 patient. Gram-positive bacillus wer
e noted on Gram-stains of material obtained from skin lesions in 2 patients
. All but one patient was successfully treated with penicillin; the unrespo
nsive patient was treated with cefuroxime and required plastic reconstructi
ve surgery because of a skin defect on the eyelid.