A stereoselective approach to isoxazolidinyl nucleosides

Authors
Chiacchio, U Corsaro, A Iannazzo, D Piperno, A Procopio, A Rescifina, A Romeo, G Romeo, R
Citation
U. Chiacchio et al., A stereoselective approach to isoxazolidinyl nucleosides, EUR J ORG C, (10), 2001, pp. 1893-1898
Citations number
41
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
1434193X → ACNP
Issue
10
Year of publication
2001
Pages
1893 - 1898
Database
ISI
SICI code
1434-193X(200105):10<1893:ASATIN>2.0.ZU;2-B
Abstract
A stereoselective approach towards isoxazolidinyl nucleosides has been desi gned. The 1,3-dipolar cycloaddition of a C-chiral nitrone with purine and p yrimidine nucleobases produces thymidine and adenine N,O-nucleosides, in en antiomerically pure forms.