Synthetic microbial chemistry, XXXVI. Synthesis and absolute configurationof (-)-neuchromenin, a neurotrophic metabolite of Eupenicillium javanicum var. meloforme, and its enantiomer

Authors
Tanada, Y Mori, K
Citation
Y. Tanada et K. Mori, Synthetic microbial chemistry, XXXVI. Synthesis and absolute configurationof (-)-neuchromenin, a neurotrophic metabolite of Eupenicillium javanicum var. meloforme, and its enantiomer, EUR J ORG C, (10), 2001, pp. 1963-1966
Citations number
10
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
1434193X → ACNP
Issue
10
Year of publication
2001
Pages
1963 - 1966
Database
ISI
SICI code
1434-193X(200105):10<1963:SMCXSA>2.0.ZU;2-Y
Abstract
Both the enantiomers of neuchromenin 1 (2,3-dihydro-8,9-dihydroxy-2-methyl- 4H,5H-pyrano[3,2-c] [1]benzopyran-4-one) were synthesized starting from the enantiomers of ethyl 3-hydoxybutanoate (7). The naturally occurring (-)-ne uchromenin, a neurotrophic metabolite of Eupenicillium javonicum var. melof orme, was shown to be (S)-1.