CHARACTERIZATION OF STEREOISOMERIC FURANOSIDIC DERIVATIVES BY DIRECT CHEMICAL-IONIZATION MASS-SPECTROMETRY AND LIQUID SECONDARY-ION MASS-SPECTROMETRY WITH TANDEM MASS-SPECTROMETRY

The present study deals with the mass spectrometric characterization o f furanosidic compounds containing a 1,2-O-isopropylidene group using different mass spectrometric techniques: chemical ionization mass spec trometry and liquid secondary ion mass spectrometry together with meta stable ion analysis and collision-induced dissociation, Common fragmen tation differences relate to the extent of the loss of mater and the e limination of acetone, It is also shown that the introduction of a sta ble charge centre (Li+) in the molecules is critical for observing a r earrangement involving hydrogen transfer in one of the two stereoisome ric pairs examined. (C) 1997 by John Wiley & Sons, Ltd.