Obesity is a disease with many comorbidities, some of which increase periop
erative risk and most of which are improved or even cured by weight loss ef
fectively achieved by surgery. Since anti-obesity surgery is 'behavioral su
rgery', outcome is independent of the technical performance of the operatio
n and patient selection is critical. Pre- and postoperative patient educati
on is more important than in other gastrointestinal surgery. For example, k
nowledge of the 'Rules of eating' and the 'Rules of vomiting' are essential
for outcome of gastric restrictive surgery.
Indications for bariatric surgery are evolving as safety is increasing and
more long-term data unequivocally demonstrate its effectiveness, leading to
adjustments downward in body mass index and minimum age. However, outcome
predictors are lacking, though it is recognized that patient knowledge, psy
chosocial adaptation and motivational factors including secondary gain and
other benefits to remaining obese are important. Discrepancies between pati
ents' weight goals,'ideal' or healthy weight for post-obese individuals and
realistic weight loss based on body composition and energy balance, contri
bute to subjective assessment of quality of life after bariatric surgery. W
ell-designed observational studies rather than randomized trials, which are
both ethically and scientifically flawed, are needed to improve patient se
lection. Until valid outcome predictors have been identified, a staged appr
oach to bariatric surgery entailing long-term reoperation rates of up to 30
% will prevail.