The purpose of this study was to histologically evaluate four teeth with re
cession defects that were treated with guided tissue regeneration (GTR). Th
e amount of root coverage obtained ranged from 16.7% to 50.0%. In one of th
e defects treated, new bone was formed but none of the new bone was coronal
to the original gingival margin. Additionally, in this one case new cement
um and connective tissue attachment was formed. However, because the new bo
ne, new cementum, and new connective tissue were not coronal to the origina
l gingival margin, this result could not be classified as regeneration. The
vast majority of the attachment in this defect was long junctional epithel
ial attachment in the portion of the recession defect covered by the root-c
overage procedure. In the other three defects treated, there was a loss of
bone. All of the root coverage obtained was a long junctional epithelial at
tachment in three of the four defects. The results of this study do not sho
w regeneration in any of the four defects treated.