SYNTHESIS AND INSECTICIDAL ACTIVITY OF NOVEL PYRIDINE METHANESULFONATES

A model has been developed which has led to the design and synthesis o f novel 6-methanesulfonyloxypyridine-2-carboxamides with insecticidal activity, low mammalian toxicity and safety to aquatic organisms. The amides formed from amines with alpha branching (e.g. isopropyl and sec -butyl) demonstrated the highest level of activity. Rice nursery box f ield test results on laboratory raised insects gave insufficient contr ol of the entire Japanese hopper spectrum to warrant further developme nt of these compounds.