PALLADIUM-CATALYZED ASYMMETRIC CYCLOCARBONYLATION OF 2-(1-METHYLVINYL)ANILINES

Authors
OKURO K KAI H ALPER H
Citation
K. Okuro et al., PALLADIUM-CATALYZED ASYMMETRIC CYCLOCARBONYLATION OF 2-(1-METHYLVINYL)ANILINES, Tetrahedron : asymmetry, 8(14), 1997, pp. 2307-2309
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
14
Year of publication
1997
Pages
2307 - 2309
Database
ISI
SICI code
0957-4166(1997)8:14<2307:PACO2>2.0.ZU;2-W
Abstract
The asymmetric cyclocarbonylation of 2-vinylanilines catalyzed by pall adium with chiral phosphines was investigated. The reaction of 2-(1-me thylvinyl)anilines using a catalyst system consisting of Pd(OAc)(2)-2( -)-DIOP gave 3,4-dihydro-4-methyl-2(1H)-quinolin-2-ones in up to 54% e nantiomeric excess. (C) 1997 Elsevier Science Ltd.