THE EFFECT OF ABSORBING RESINS ON SUBSTRATE CONCENTRATION AND ENANTIOMERIC EXCESS IN YEAST REDUCTION

Authors
DARRIGO P FANTONI GP SERVI S STRINI A
Citation
P. Darrigo et al., THE EFFECT OF ABSORBING RESINS ON SUBSTRATE CONCENTRATION AND ENANTIOMERIC EXCESS IN YEAST REDUCTION, Tetrahedron : asymmetry, 8(14), 1997, pp. 2375-2379
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
14
Year of publication
1997
Pages
2375 - 2379
Database
ISI
SICI code
0957-4166(1997)8:14<2375:TEOARO>2.0.ZU;2-A
Abstract
The correlation between the enantiomeric excess (e.e.) of the (S)-(+)- ethyl-3-hydroxybutanoate 2, obtained in the baker's yeast reduction of ethyl acetoacetate 1, and the concentration of the substrates in the fermentation mixture has been studied by the use of two different tech niques (absorbing resins and organic solvents) The presence of resins undoubtedly influences the enantiomeric excess of the product. (C) 199 7 Elsevier Science Ltd.