ENANTIOSELECTIVE SYNTHESIS OF NOVEL, HIGHLY CONFORMATIONALLY CONSTRAINED PEPTIDE SURROGATES

Authors
DIAZ M JIMENEZ JM ORTUNO RM
Citation
M. Diaz et al., ENANTIOSELECTIVE SYNTHESIS OF NOVEL, HIGHLY CONFORMATIONALLY CONSTRAINED PEPTIDE SURROGATES, Tetrahedron : asymmetry, 8(14), 1997, pp. 2465-2471
Citations number
37
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
14
Year of publication
1997
Pages
2465 - 2471
Database
ISI
SICI code
0957-4166(1997)8:14<2465:ESONHC>2.0.ZU;2-T
Abstract
Two new enantiomeric peptide surrogates as well as a tripeptide, ail o f them having highly conformationally constrained structures, have bee n synthesized. (Z)-cyclo-Aspartic acid and convenient a-substituted is oserine derivatives, in both antipodal forms, as well as methyl (R)-2- phenylglycinate, have been used as the monomeric units. (C) 1997 Elsev ier Science Ltd.