CAMPHORSULFONAMIDE DERIVATIVES - A NEW CLASS OF CHIRAL CATALYSTS FOR THE TITANIUM ALKOXIDE-PROMOTED ADDITION OF DIALKYLZINC TO ALDEHYDES

Authors
RAMON DJ YUS M
Citation
Dj. Ramon et M. Yus, CAMPHORSULFONAMIDE DERIVATIVES - A NEW CLASS OF CHIRAL CATALYSTS FOR THE TITANIUM ALKOXIDE-PROMOTED ADDITION OF DIALKYLZINC TO ALDEHYDES, Tetrahedron : asymmetry, 8(14), 1997, pp. 2479-2496
Citations number
73
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
14
Year of publication
1997
Pages
2479 - 2496
Database
ISI
SICI code
0957-4166(1997)8:14<2479:CD-ANC>2.0.ZU;2-G
Abstract
The enantioselective addition of dialkylzinc to several aldehydes, usi ng different chiral bidentate ligands (3a-j, 4a-h) [derived from (+)-1 0-camphorsulfonyl chloride] and titanium alkoxide as catalysts, is stu died. The influence of temperature, titanium alkoxide, stoichiometry, additive, aldehyde and ligand structure is also studied. (C) 1997 Else vier Science Ltd.