ALTERATIONS IN SUPEROXIDE-DISMUTASE ISOZYMES BY METHYLMERCURY

Authors
KUMAGAI Y HOMMATAKEDA S SHINYASHIKI M SHIMOJO N
Citation
Y. Kumagai et al., ALTERATIONS IN SUPEROXIDE-DISMUTASE ISOZYMES BY METHYLMERCURY, Applied organometallic chemistry, 11(8), 1997, pp. 635-643
Citations number
62
Categorie Soggetti
Chemistry Applied","Chemistry Inorganic & Nuclear
Journal title
Applied organometallic chemistry → ACNP
ISSN journal
02682605
Volume
11
Issue
8
Year of publication
1997
Pages
635 - 643
Database
ISI
SICI code
0268-2605(1997)11:8<635:AISIBM>2.0.ZU;2-W
Abstract
A study of alterations in two mammalian superoxide dismutases (SODs), Cu,Zn-SOD and Mn-SOD, caused by methylmercury has been reviewed, Mecha nisms for the isozyme-selective decrease in MnSOD activity by the orga nometallic compound observed in vivo have been extensively examined by experiments with purified enzyme preparations. (C) 1997 by John Wiley & Sons, Ltd.