Calcium oxalate granuloma of the nose of a chronically dialysed nephritic patient

The patient was a 54-year-old woman who had been suffering from chronic tub ulo-interstitial nephritis fur about seven years, requiring haemodialysis. More recently, she developed a polypoid mass in the left nasal cavity causi ng discomfort on breathing and slight epistaxis. The tumour was of gritty c onsistency and measured 28 x 8 x 5 mm. Microscopy showed a lobulated almost cystic structure composed of granulation tissue with comparatively few pla sma cells and many multinucleated giant cells lining the spaces filled with crystalline deposits of calcium oxalate.