A simple method for constructing microinjectrodes for reversible inactivation in behaving monkeys

A method for constructing a simple, durable injection-microelectrode (injec trode) is described. The injectrode can record neuronal activity, stimulate neuronal tissues, or inject substances locally through its tip. The inject rode is lightweight and is easy to construct from commercially available pa rts, and it can be used repeatedly for multiple recordings and injections. Since dura penetration can damage fragile electrode tips, a reliable method to pass the injectrode through an intact dura matter is described. (C) 200 1 Elsevier Science B.V. All rights reserved.