Hydrophobicity is considered to be a phenomenon that nonpolar solutes have
a poor solubility in water? which plays fundamental roles in many chemical
and biological systems. On the basis of the scaled particle theory, it has
been shown in the present study that hydrophobicity is not caused by the sm
all size of water molecules but by their high packing density generated fro
m strong molecular interaction, Solvophobicity, observed in some organic so
lvents such as ethylene glycol, can be also explained consistently by the p
resent method.