Kc. Hu et al., Multiple myeloma associated with extramedullary plasmacytoma causing nerveroot compression: A case report, J FORMOS ME, 100(4), 2001, pp. 277-280
Multiple myeloma associated with extramedullary plasmacytoma at initial pre
sentation is rare. We describe a 45-year-old female patient with an initial
presentation of low back pain and right side L5, S1 radiculopathy. There w
as no evidence of vertebral involvement but an epidural tumor was found lat
er during neurosurgical intervention. The final diagnosis was immunoglobuli
n G, kappa multiple myeloma complicated with spinal root compression by an
extramedullary plasmacytoma, No osteolytic lesion was noted over the length
of the spine. Pathology revealed high grade plasmablastic myeloma. During
the clinical course, the patient was refractory to induction chemotherapy,
and there was progressive deterioration of renal function. Urinary tract in
fection by Morganella morganii and pulmonary infection of unknown cause dev
eloped 5 months later, and the patient died.