Multiple myeloma associated with extramedullary plasmacytoma causing nerveroot compression: A case report

Citation
Kc. Hu et al., Multiple myeloma associated with extramedullary plasmacytoma causing nerveroot compression: A case report, J FORMOS ME, 100(4), 2001, pp. 277-280
Citations number
21
Categorie Soggetti
General & Internal Medicine
Journal title
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
ISSN journal
09296646 → ACNP
Volume
100
Issue
4
Year of publication
2001
Pages
277 - 280
Database
ISI
SICI code
0929-6646(200104)100:4<277:MMAWEP>2.0.ZU;2-1
Abstract
Multiple myeloma associated with extramedullary plasmacytoma at initial pre sentation is rare. We describe a 45-year-old female patient with an initial presentation of low back pain and right side L5, S1 radiculopathy. There w as no evidence of vertebral involvement but an epidural tumor was found lat er during neurosurgical intervention. The final diagnosis was immunoglobuli n G, kappa multiple myeloma complicated with spinal root compression by an extramedullary plasmacytoma, No osteolytic lesion was noted over the length of the spine. Pathology revealed high grade plasmablastic myeloma. During the clinical course, the patient was refractory to induction chemotherapy, and there was progressive deterioration of renal function. Urinary tract in fection by Morganella morganii and pulmonary infection of unknown cause dev eloped 5 months later, and the patient died.