Synthesis and in vitro antitumor activity of triarylantimony di(triphenylgermanyl)propionates

Authors
Ma, YQ Li, JS
Citation
Yq. Ma et Js. Li, Synthesis and in vitro antitumor activity of triarylantimony di(triphenylgermanyl)propionates, MAIN GR MET, 24(4), 2001, pp. 235-238
Citations number
18
Categorie Soggetti
Chemistry
Journal title
MAIN GROUP METAL CHEMISTRY
ISSN journal
07921241 → ACNP
Volume
24
Issue
4
Year of publication
2001
Pages
235 - 238
Database
ISI
SICI code
0792-1241(2001)24:4<235:SAIVAA>2.0.ZU;2-4
Abstract
A series of novel triarylantimony (V) di(triphenylgermanyl)propionates with the general formula ((Ph3GeCHRCHRCO2)-C-1-C-2)(2)SbAr3 (R-1 = H, Ph; R-2 = H, CH3) were synthesized by the reaction of Ar3SbBr2 with triphenylgermany lpropionic acid in the presence of triethylanaine. The in vitro antitumor a ctivities of the title compounds against the five cancer lines are reported .