Syngeneic consecutive rat spleen transplantation bearing infantile testis

Seventy-seven Lewis adult rats received autologous testicular implants in t he spleen. These spleens were retransplanted in a consecutive transplant fa shion as we described earlier, Some were observed as long as 26 to 27 month s. Although earlier splenic-testicular transplants showed benign granulosa cell tumors, some of the long-term follow-ups showed a seminoma-like transf ormation. (C) 2001 Wiley-Liss, Inc.