Models of frequency preferences of prefrontal cortical neurons

Citation
Ar. Houweling et al., Models of frequency preferences of prefrontal cortical neurons, NEUROCOMPUT, 38, 2001, pp. 231-238
Citations number
10
Categorie Soggetti
AI Robotics and Automatic Control
Journal title
NEUROCOMPUTING
ISSN journal
09252312 → ACNP
Volume
38
Year of publication
2001
Pages
231 - 238
Database
ISI
SICI code
0925-2312(200106)38:<231:MOFPOP>2.0.ZU;2-P
Abstract
The reliability of spike trains generated by sinusoidal current injections in prefrontal cortical pyramidal cells and interneurons depends strongly on the input frequency. We constructed computational models in order to study how cellular properties affect reliability. The models reproduced the main experimental findings: subthreshold oscillations, resonance and reliabilit y of spike timing. The amplitude of intrinsic noise in the model determined the number of reliable frequency bands. In addition, the frequency content of the noise did not affect reliability. (C) 2001 Elsevier Science B.V. Al l rights reserved.