Diabetes mellitus (DM) is a major risk factor for cardiovascular disease (C
VD) in men and women. Type 2 is the most prevalent form of DM and is associ
ated with a two to threefold increased risk of CVD morbidity and mortality.
Insulin resistance, the fundamental defect of type 2 DM, is associated wit
h a cluster of cardiovascular risk factors, one of which is dyslipidemia. T
his article discusses CVD risk in DM, characteristics of the atherogenic dy
slipidemia, screening for abnormal lipids, clinical trial evidence for trea
tment of hyperlipidemia, and treatment approaches.