Vitamin A plays an important role in the pathogenesis and during the course
of retinal degenerations. Following a brief overview of the metabolic path
way of Vitamin A from the entrance into the body to the arrival in retinal
target structures, the most important retinal degenerations that are relate
d to the Vitamin A-metabolism are presented. Ways of prevention or therapy
of such diseases are discussed in the light of the still incomplete knowled
ge about basic mechanisms of retinol transport and metabolism.