Vitamin-A metabolism and retinal degeneration

Citation
M. Seeliger et Hk. Biesalski, Vitamin-A metabolism and retinal degeneration, OPHTHALMOLO, 98(6), 2001, pp. 520-525
Citations number
28
Categorie Soggetti
Optalmology
Journal title
OPHTHALMOLOGE
ISSN journal
0941293X → ACNP
Volume
98
Issue
6
Year of publication
2001
Pages
520 - 525
Database
ISI
SICI code
0941-293X(200106)98:6<520:VMARD>2.0.ZU;2-N
Abstract
Vitamin A plays an important role in the pathogenesis and during the course of retinal degenerations. Following a brief overview of the metabolic path way of Vitamin A from the entrance into the body to the arrival in retinal target structures, the most important retinal degenerations that are relate d to the Vitamin A-metabolism are presented. Ways of prevention or therapy of such diseases are discussed in the light of the still incomplete knowled ge about basic mechanisms of retinol transport and metabolism.