Successful treatment of Acanthamoeba meningitis with combination oral antimicrobials

Authors
Singhal, T Bajpai, A Kalra, V Kabra, SK Samantaray, JC Satpathy, G Gupta, AK
Citation
T. Singhal et al., Successful treatment of Acanthamoeba meningitis with combination oral antimicrobials, PEDIAT INF, 20(6), 2001, pp. 623-627
Citations number
34
Categorie Soggetti
Clinical Immunolgy & Infectious Disease
Journal title
PEDIATRIC INFECTIOUS DISEASE JOURNAL
ISSN journal
08913668 → ACNP
Volume
20
Issue
6
Year of publication
2001
Pages
623 - 627
Database
ISI
SICI code
0891-3668(200106)20:6<623:STOAMW>2.0.ZU;2-L
Abstract
Acanthamoeba was implicated as the causative agent of chronic meningitis in three apparently immunocompetent children. Diagnosis was established by ce rebrospinal fluid wet mount examination and culture. Two children improved rapidly with combination oral therapy composed of trimethoprim-sulfamethoxa zole, rifampin and ketoconazole.