The insufficient number of suitable cadaveric organs for pediatric recipien
ts is the cause of high pretransplant mortality rates and long waiting time
s. With the introduction of split and living related liver transplantation,
the waiting list mortality rate has dropped from greater than 15% to less
than 5% and children are transplanted more rapidly. A 5-year patient and gr
aft survival rate of greater than 80% has been obtained in those centers wh
ere split and living related liver transplantations are routinely performed
. The data analyzed in this paper show that the only current solution to ca
daveric organ shortage is a 'multimodal' approach. where whole liver cadave
ric transplantation is associated with split and living related liver trans
plantation.