Long-term outcomes of immunosuppressed renal transplant recipients with malignancies

This study analyzes ten cases of malignancy in a cohort of 183 renal transp lant recipients, examining surgical management, postoperative immunosuppres sive therapy, and long-term outcome. One of these ten patients, who had mal ignant lymphoma of the jejunum, died of the neoplasm, but the other nine pa tients did not show any signs of tumor recurrence after removal. All of the se nine patients, except for one who had transplant renal cell carcinoma (R CC), received the same dose of immunosuppressive agents after surgery for t he malignant disease. Seven patients were still alive at the time of this r eport, six of whom had good transplant renal function. The findings of this study indicate that even if immunosuppressive agents predispose to the dev elopment of cancer, it is not necessary to reduce their dose after removal of the tumor.