Ferrocenyl thiolates as ligands in the enantioselective copper-catalyzed substitution of allylic acetates with Grignard reagents

Authors
Karlstrom, ASE Huerta, FF Meuzelaar, GJ Backvall, JE
Citation
Ase. Karlstrom et al., Ferrocenyl thiolates as ligands in the enantioselective copper-catalyzed substitution of allylic acetates with Grignard reagents, SYNLETT, 2001, pp. 923-926
Citations number
49
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Year of publication
2001
Pages
923 - 926
Database
ISI
SICI code
0936-5214(2001):<923:FTALIT>2.0.ZU;2-8
Abstract
The application of ferrocenyl thiolates as ligands in copper-catalyzed asym metric substitution reactions of allylic acetates with Grignard reagents is reported. The catalyst formed from lithium thiolate 12 gave the gamma -pro ducts in high selectivity and with up to 64% ee.