Clinical criteria to recognize subjects with cognitive impairment in the pr
e-dementia stage are becoming available. These are frail subjects, at risk
of adverse outcomes, such as death, institutionalization, and functional an
d cognitive deterioration. Early identification of these subjects has a gre
at importance in order to start rehabilitative or pharmacological intervent
ions that could slow the progression of cognitive impairment, and the onset
of disability. In this regard, cognitive screening tests might be helpful
in different clinical settings (general practice, acute care, rehabilitatio
n, and nursing home). We describe the most frequent clinical presentations
of cognitive impairment in the pre-dementia stage, and review eleven screen
ing tests to provide recommendations on which should be preferred in each s
etting. (C) 2001, Editrice Kurtis.