Objective. The purpose of this study was to determine the diagnostic accura
cy of CT in detecting mandibular invasion by squamous cell carcinoma of the
oral cavity.
Materials and methods. Forty-nine patients who had squamous cell carcinoma
of the oral cavity that was clinically fixed to the mandible were treated w
ith mandibulectomy. All patients underwent contrast-enhanced CT (contiguous
3-mm-thick sections) through the primary site before surgery. All studies
were reconstructed with bone algorithm. These studies were retrospectively
reviewed by a neuroradiologist for evidence of mandibular invasion. The ima
ging results were compared with the histologic findings in all cases.
Results. CT correctly revealed 25 of 26 cases with mandibular invasion. CT
correctly excluded mandibular invasion in 20 of 23 cases without invasion.
The diagnostic accuracy of CT for detecting mandibular invasion was as foll
ows: sensitivity, 96%; specificity, 87%; positive predictive value, 89%; an
d negative predictive value, 95%.
Conclusion. Thin-section (3-mm) CT reconstructed with bone algorithm is an
accurate technique to detect mandibular involvement by squamous cell carcin
oma of the oral cavity.