CT detection of mandibular invasion by squamous cell carcinoma of the oralcavity

Citation
Sk. Mukherji et al., CT detection of mandibular invasion by squamous cell carcinoma of the oralcavity, AM J ROENTG, 177(1), 2001, pp. 237-243
Citations number
23
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Medical Research Diagnosis & Treatment
Journal title
AMERICAN JOURNAL OF ROENTGENOLOGY
ISSN journal
0361803X → ACNP
Volume
177
Issue
1
Year of publication
2001
Pages
237 - 243
Database
ISI
SICI code
0361-803X(200107)177:1<237:CDOMIB>2.0.ZU;2-E
Abstract
Objective. The purpose of this study was to determine the diagnostic accura cy of CT in detecting mandibular invasion by squamous cell carcinoma of the oral cavity. Materials and methods. Forty-nine patients who had squamous cell carcinoma of the oral cavity that was clinically fixed to the mandible were treated w ith mandibulectomy. All patients underwent contrast-enhanced CT (contiguous 3-mm-thick sections) through the primary site before surgery. All studies were reconstructed with bone algorithm. These studies were retrospectively reviewed by a neuroradiologist for evidence of mandibular invasion. The ima ging results were compared with the histologic findings in all cases. Results. CT correctly revealed 25 of 26 cases with mandibular invasion. CT correctly excluded mandibular invasion in 20 of 23 cases without invasion. The diagnostic accuracy of CT for detecting mandibular invasion was as foll ows: sensitivity, 96%; specificity, 87%; positive predictive value, 89%; an d negative predictive value, 95%. Conclusion. Thin-section (3-mm) CT reconstructed with bone algorithm is an accurate technique to detect mandibular involvement by squamous cell carcin oma of the oral cavity.