Short report: IgGI/IgG3 antibody responses to various analogs of recombinant yPfMSPl(19) - A study in immune adults living in areas of Plasmodium falciparum transmission

Authors
Diallo, TO Spiegel, A Diouf, A Perraut, R Kaslow, DC Garraud, O
Citation
To. Diallo et al., Short report: IgGI/IgG3 antibody responses to various analogs of recombinant yPfMSPl(19) - A study in immune adults living in areas of Plasmodium falciparum transmission, AM J TROP M, 64(3-4), 2001, pp. 204-206
Citations number
14
Categorie Soggetti
Envirnomentale Medicine & Public Health","Medical Research General Topics
Journal title
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
ISSN journal
00029637 → ACNP
Volume
64
Issue
3-4
Year of publication
2001
Pages
204 - 206
Database
ISI
SICI code
0002-9637(200103/04)64:3-4<204:SRIART>2.0.ZU;2-N
Abstract
To further characterize protective-type (IgG1/IgG3) antibody responses to P lasmodium falciparum blood stage in putatively immune individuals' plasma, we have tested for various analogs of the 19 kDa C-terminus of the MSP1 ant igen obtained as secreted recombinant proteins from Saccharomyces cerevisia e. One of four proteins was then identified on the basis of consistent IgG3 , along with less variable IgG1 recognition. This protein has thus been sel ected for further functional assays of IgG1/IgG3 antibodies.