Synthesis, characterization, coordination and antibacterial properties of novel asymmetric 1,1 '-disubstituted ferrocene-derived Schiff-base ligands and their Co(II), Cu(II) Ni(II) and Zn(II) complexes

Some new asymmetric 1.1'-disubstituted ferrocene-derived Schiff-bases have been prepared and used as ligands in the preparation of their Co(II), Cu(II ), NI(II) and Zn(II) metal chelates. These synthesized ligands and their me tal chelates have been characterized by their physical, analytical and spec tral data. These have also been used for screening against pathogenic bacte rial species, e.g. Escherichia coli, Staphylococcus aureus, Pseudomonas aer uginosa and Klebsiella pneumonae and have been found to be a novel class of organometallic-based antibacterials, Copyright (C) 2001 John Wiley & Sons, Ltd.