The changes in cellular composition of the milk of the koala (Phascolarctos
cinereus) have been investigated in late lactation and after the loss of p
ouch and back young. During lactation, the polymorphonuclear neutrophil was
the most frequently observed cell. After loss or removal of the young, mac
rophages and foamy epithelial cells were detected in moderate to high numbe
rs. In one animal, mammary secretions containing lymphocytes and unidentifi
able, immature mononuclear cells continued for 120 days after the loss of p
ouch young. These observations of cellular composition of late- and post-la
ctation secretions are consistent with reports from a number of eutherian m
ammals and also with another marsupial, the tammar wallaby (Macropus eugeni
i).