Role of reactive oxygen species in cell signalling pathways

Authors
Hancock, JT Desikan, R Neill, SJ
Citation
Jt. Hancock et al., Role of reactive oxygen species in cell signalling pathways, BIOCH SOC T, 29, 2001, pp. 345-350
Citations number
50
Categorie Soggetti
Biochemistry & Biophysics
Journal title
BIOCHEMICAL SOCIETY TRANSACTIONS
ISSN journal
03005127 → ACNP
Volume
29
Year of publication
2001
Part
2
Pages
345 - 350
Database
ISI
SICI code
0300-5127(200105)29:<345:ROROSI>2.0.ZU;2-N
Abstract
Reactive oxygen species (ROS) were originally thought to only be released b y phagocytic cells during their role in host defence. It is now clear that ROS have a cell signalling role in many biological systems, both in animals and in plants. ROS induce programmed cell death or necrosis, induce or sup press the expression of many genes, and activate cell signalling cascades, such as those involving mitogen-activated protein kinases.