Biphenyls as surrogates of the steroidal backbone. Part 1: Synthesis and estrogen receptor affinity of an original series of polysubstituted biphenyls

Authors
Lesuisse, D Albert, E Bouchoux, F Cerede, E Lefrancois, JM Levif, MO Tessier, S Tric, B Teutsch, G
Citation
D. Lesuisse et al., Biphenyls as surrogates of the steroidal backbone. Part 1: Synthesis and estrogen receptor affinity of an original series of polysubstituted biphenyls, BIOORG MED, 11(13), 2001, pp. 1709-1712
Citations number
43
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
11
Issue
13
Year of publication
2001
Pages
1709 - 1712
Database
ISI
SICI code
0960-894X(20010709)11:13<1709:BASOTS>2.0.ZU;2-J
Abstract
In the course of a programme aimed at discovering nea ligands of the estrog en receptor, we explored a series of substituted biphenyls. Their synthesis and binding affinity are described. (C) 2001 Elsevier Science Ltd. All rig hts reserved.