Distribution of various calcium channel alpha(1) subunits in murine DRG neurons and antinociceptive effect of omega-conotoxin SVIB in mice

Authors
Murakami, M Suzuki, T Nakagawasai, O Murakami, H Murakami, S Esashi, A Taniguchi, R Yanagisawa, T Tan-No, K Miyoshi, I Sasano, H Tadano, T
Citation
M. Murakami et al., Distribution of various calcium channel alpha(1) subunits in murine DRG neurons and antinociceptive effect of omega-conotoxin SVIB in mice, BRAIN RES, 903(1-2), 2001, pp. 231-236
Citations number
27
Categorie Soggetti
Neurosciences & Behavoir
Journal title
BRAIN RESEARCH
ISSN journal
00068993 → ACNP
Volume
903
Issue
1-2
Year of publication
2001
Pages
231 - 236
Database
ISI
SICI code
0006-8993(20010608)903:1-2<231:DOVCCA>2.0.ZU;2-S
Abstract
Immunohistological study revealed the differential localization of subtypes of voltage-dependent calcium channels in the dorsal root ganglion neurons. Intrathecal injection of omega -conotoxin SVIB, an analogue of omega -cono toxin GVIA, which acts on N-type voltage-dependent calcium channels, signif icantly shortened the licking time in the late phase of a formalin test. (C ) 2001 Elsevier Science B.V. All rights reserved.