D. Cummins et al., Chronic disseminated intravascular coagulation after surgery for abdominalaortic aneurysm: clinical and haemostatic response to dalteparin, BR J HAEM, 113(3), 2001, pp. 658-660
A 77-year-old man developed chronic disseminated intravascular coagulation
(DIC) after surgical repair of a large infrarenal aortic aneurysm, Self-adm
inistered subcutaneous dalteparin therapy (5000 units o.d.) led to rapid re
lief of symptoms and sustained improvements in his platelet count and fibri
nogen level; activation of coagulation and fibrinolysis appeared to be rela
tively unaffected. Long-term treatment with low-molecular-weight heparin ca
n provide good symptomatic control of chronic DIC associated with abdominal
aortic aneurysm.