Stereoselective construction of trans-1,2-benzooxadecaline frameworks by three-component cascade reactions of an alpha-phenethyl-beta-borylallylsilane with aldehydes

Authors
Suginome, M Ohmori, Y Ito, Y
Citation
M. Suginome et al., Stereoselective construction of trans-1,2-benzooxadecaline frameworks by three-component cascade reactions of an alpha-phenethyl-beta-borylallylsilane with aldehydes, CHEM COMMUN, (12), 2001, pp. 1090-1091
Citations number
15
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
12
Year of publication
2001
Pages
1090 - 1091
Database
ISI
SICI code
1359-7345(20010621):12<1090:SCOTFB>2.0.ZU;2-P
Abstract
Reactions of alpha -phenethyl-beta -borylallylsilane with aldehydes afforde d tricyclic trans- 1,2-benzooxadecaline frameworks stereoselectively in the presence of Lewis acids via sequential incorporation of two different alde hydes followed by cationic cascade cyclization, ending up with intramolecul ar Friedel-Crafts reaction.