The first lower-rim full O-pyridyl and O-quinolyl ether derivatives of cali
x[4]arene and p-tert-butylcalix[4]arene in 1,3-alternate conformation have
been synthesized using cesium carbonate as a promoter at high reaction temp
erature and their structures and conformations were characterized by H-1 NM
R spectra and X-ray crystallography.