Chiral camphor derivatives as new catalysts for asymmetric phase-transfer alkylation

Citation
J. Zhang et al., Chiral camphor derivatives as new catalysts for asymmetric phase-transfer alkylation, CHIN J CHEM, 19(6), 2001, pp. 630-633
Citations number
32
Categorie Soggetti
Chemistry
Journal title
CHINESE JOURNAL OF CHEMISTRY
ISSN journal
1001604X → ACNP
Volume
19
Issue
6
Year of publication
2001
Pages
630 - 633
Database
ISI
SICI code
1001-604X(200106)19:6<630:CCDANC>2.0.ZU;2-E
Abstract
The synthesis of new chiral phase-transfer catalysts based on the optical c amphor is described. The alkylation of the benzophenone imine of glycine te rt-butyl ester with benzyl bromide in the presence of new chiral phase-tran sfer catalysts afforded the desired alkylation product in good yields and u p to 39% ee.