A possible mode of the specific recognition of nucleic acids by proteins

Authors
Li, XQ Liu, CQ
Citation
Xq. Li et Cq. Liu, A possible mode of the specific recognition of nucleic acids by proteins, CHIN SCI B, 46(11), 2001, pp. 930-934
Citations number
17
Categorie Soggetti
Multidisciplinary
Journal title
CHINESE SCIENCE BULLETIN
ISSN journal
10016538 → ACNP
Volume
46
Issue
11
Year of publication
2001
Pages
930 - 934
Database
ISI
SICI code
1001-6538(200106)46:11<930:APMOTS>2.0.ZU;2-Y
Abstract
Seven sets of protein target sites, which occur in several gene promoters, have been analyzed. The results suggest that there is a possible mode of sp ecific recognition of double-helical nucleic acids by proteins, This recogn ition mode is related to a special topological property of double-helical D NA, which is termed base spatial pattern (BSP) of DNA segment. BSP is the s patial topological property determined only by the spatial arrangement of t he bases on double-helical DNA segment.