Peripheral nonulcerative keratitis as a presenting sign of microscopic polyangiitis

Purpose. To report a 16-year-old woman who had peripheral keratitis as a pr esenting sign of microscopic polyangiitis (MPA), which rapidly progressed t o acute renal failure. Method. Case report. Results, The patient's vasculit is was diagnosed by renal biopsy, which was evaluated with histologic, immu nofluorescence, and electron microscopy. The diagnosis was confirmed by lab oratory study, which showed a positive antimyeloperoxidase antibody. Conclu sion, MPA may rarely present with ocular findings and should be considered in the differential diagnosis when a patient has peripheral keratitis.