Conjunctival necrobiotic granuloma in xeroderma pigmentosum

Purpose. We report clinical and histopathologic findings of a conjunctival lesion associated with xeroderma pigmentosum. Methods. A Saudi girl with kn own xeroderma pigmentosum presented with pain and photophobia of the right eye and an elevated temporally located perilimbal mass. Results. The mass w as resected successfully and has not recurred during 1-year follow-up. Hist opathologic examination of the tissue showed a necrobiotic granuloma with a ssociated histiocytic infiltration. The patient had no systemic disease, li pid was not detected in the histiocytic lesion, no Touton giant cells were present, and there was no evidence of elastolysis. Conclusion. Ocular malig nancies occur in association with xeroderma pigmentosum, but benign lesions that mimic a malignancy may occur.