In this study we examined the presence of cannabinoids in saliva samples ob
tained from 24 drug-abusers. The saliva specimens were collected by "EPITOP
E" system and the subsequent elution of samples was achieved by centrifugat
ion. The resulting ultrafiltrates have been directly sampled with solid pha
se micro-extraction (SPME) and then analyzed by GC/MS. Saliva sampling is l
ess invasive than collection of blood. (C) 2001 Elsevier Science Ireland Lt
d. All rights reserved.