Microwave-accelerated Suzuki cross-coupling reaction in polyethylene glycol (PEG)

Authors
Namboodiri, VV Varma, RS
Citation
Vv. Namboodiri et Rs. Varma, Microwave-accelerated Suzuki cross-coupling reaction in polyethylene glycol (PEG), GREEN CHEM, 3(3), 2001, pp. 146-148
Citations number
23
Categorie Soggetti
Chemistry
Journal title
GREEN CHEMISTRY
ISSN journal
14639262 → ACNP
Volume
3
Issue
3
Year of publication
2001
Pages
146 - 148
Database
ISI
SICI code
1463-9262(200106)3:3<146:MSCRIP>2.0.ZU;2-F
Abstract
Polyethylene glycol (PEG) is found to be an inexpensive and non-toxic react ion medium for the microwave-assisted Suzuki cross-coupling of arylboronic acids with aryl halides. This environmentally friendly microwave protocol o ffers ease of operation and enables recyclability of catalyst and synthesis of a variety of substituted biaryls employing palladium chloride as cataly st and potassium fluoride as the base.