Prognostic factors for survival in invasive squamous cell vulvar carcinoma: A univariate analysis

The charts of 50 women with invasive squamous cell vulvar carcinoma were re viewed retrospectively, and pathologic, medical and life style factors were analyzed for their possible influence on survival using the Cox regression univariate model. The median age of the cohort was 73.5 years. The patient distribution according to stage was as follows: stage I: 17; stage II: 16; stage III: 12, and stage IVa: 5 patients. The median follow-up was 61 mont hs. The univariate analysis revealed that the overall survival was decrease d by age greater than or equal to 73.5 years (p = 0.0185), advanced stage ( p = 0.0026), grade III differentiation (p < 0.0001), ulcerative type of the tumor (p = 0.0055), tumor diameter > 40 mm (p = 0.0053), obesity (p = 0.01 1), smoking (p = 0.0177), diabetes (p = 0.0122) and hypertension (p = 0.044 ), but not with clitoral involvement. Copyright (C) 2001 S. Karger AG. Base l.